[CAS NO. 98796-51-1] DMT-dT Phosphoramidite

Name: DMT-dT Phosphoramidite
Brand: Arctom Scientific
SKU: HY-W013068

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PRODUCTS SPECIFICATIONS [98796-51-1]

Distributor

Catalog

HY-W013068

Brand

MCE

CAS

98796-51-1

DESCRIPTION [98796-51-1]

Overview

MDL	MFCD00055063
Molecular Weight	744.81
Molecular Formula	C40H49N4O8P
SMILES	COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@H]4O[C@@H](N5C(NC(C(C)=C5)=O)=O)C[C@@H]4OP(OCCC#N)N(C(C)C)C(C)C

For research use only. We do not sell to patients.

Summary

DMT-dT Phosphoramidite is typically used in the synthesis of DNA ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 335.66 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.3426 mL	6.7131 mL	13.4262 mL
5 mM	0.2685 mL	1.3426 mL	2.6852 mL
10 mM	0.1343 mL	0.6713 mL	1.3426 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: 2.08 mg/mL (2.79 mM); Suspended solution; Need ultrasonic
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (2.79 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] James D Thorpe, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26(41):8857-8861.

Synonyms

Thymidine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

Thymidine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

DMT-dT phosphoramidite

5′-O-DMT-thymidine 3′-CE phosphoramidite

DT-CE phosphoramidite

5′-O-(4,4′-Dimethoxytriyl)thymidine 3′-(2-cyanoethyl)-N,N-diisopropylphosphoramidite

5′-O-(4,4′-Dimethoxytrityl)thymidine 3′-(2-cyanoethyl-N,N-diisopropylphosphoramidite)

Thymidine phosphoramidite