[CAS NO. 71989-14-5] Fmoc-Asp(OtBu)-OH

Name: Fmoc-Asp(OtBu)-OH
Brand: Arctom Scientific
SKU: HY-Y1169

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PRODUCTS SPECIFICATIONS [71989-14-5]

Distributor

Catalog

HY-Y1169

Brand

MCE

CAS

71989-14-5

DESCRIPTION [71989-14-5]

Overview

MDL	MFCD00037131
Molecular Weight	411.45
Molecular Formula	C23H25NO6
SMILES	C(OC(N[C@@H](CC(OC(C)(C)C)=O)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

For research use only. We do not sell to patients.

Summary

Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 121.52 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4304 mL	12.1521 mL	24.3043 mL
5 mM	0.4861 mL	2.4304 mL	4.8609 mL
10 mM	0.2430 mL	1.2152 mL	2.4304 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (5.06 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (5.06 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Esquivel J B, et al. Chiral HPLC separation of protected amino acids. Journal of liquid chromatography & related technologies, 1998, 21(6): 777-791.

Synonyms

L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) ester

N-(9-Fluorenylmethoxycarbonyl)-L-aspartic acid β-tert-butyl ester

N-(9-Fluorenylmethoxycarbonyl)aspartic acid 4-tert-butyl ester

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-tert-butoxy-4-oxo-butanoic acid

(2S)-4-tert-Butoxy-2-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]-4-oxobutanoic acid

4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate

Fmoc-L-Asp(OtBu)-OH

Fmoc-Asp(tBu)-OH

Fmoc-L-Asp(OtBu)

(2S)-4-(tert-Butoxy)-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)-4-oxobutanoic acid

(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-[(2-methylpropan-2-yl)oxy]-4-oxobutanoic acid

(2S)-4-tert-Butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoic acid