[CAS NO. 6879-05-6] Dehydrotrametenolic acid
PRODUCTS SPECIFICATIONS [6879-05-6]
DESCRIPTION [6879-05-6]
Overview
| MDL | MFCD29048530 |
|---|---|
| Molecular Weight | 468.71 |
| Molecular Formula | C31H48O3 |
| SMILES | C[C@]12C3=CC[C@](C(C)([C@@H](O)CC4)C)([H])[C@@]4(C)C3=CC[C@@]1([C@]([C@H](C(O)=O)CCC(C(C)C)=C)([H])CC2)C |
Summary
Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos . Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects [1] .
IC50 & Target
|
Caspase-3 |
In Vitro
Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed cells with a GI 50 value of 40 μM [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Source
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 1 mg/mL ( 2.13 mM ; ultrasonic and warming and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.1335 mL | 10.6676 mL | 21.3352 mL |
| 5 mM | --- | --- | --- |
| 10 mM | --- | --- | --- |
Synonyms
