[CAS NO. 6035-49-0] Dimethylfraxetin
PRODUCTS SPECIFICATIONS [6035-49-0]
DESCRIPTION [6035-49-0]
Overview
| MDL | MFCD00145039 |
|---|---|
| Molecular Weight | 236.22 |
| Molecular Formula | C12H12O5 |
| SMILES | O=C1C=CC2=CC(OC)=C(OC)C(OC)=C2O1 |
Summary
Dimethylfraxetin is a Carbonic anhydrase inhibitor, with a K i value of 0.0097 μM.
IC50 & Target
Ki: 0.0097 μM (Carbonic anhydrase) [1]
In Vitro
At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Source
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 125 mg/mL ( 529.17 mM ; Need ultrasonic and warming)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.2333 mL | 21.1667 mL | 42.3334 mL |
| 5 mM | 0.8467 mL | 4.2333 mL | 8.4667 mL |
| 10 mM | 0.4233 mL | 2.1167 mL | 4.2333 mL |
Synonyms
