[CAS NO. 346656-34-6]  HSL-IN-3

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PRODUCTS SPECIFICATIONS [346656-34-6]

Distributor
Catalog
HY-23524
Brand
MCE
CAS
346656-34-6

DESCRIPTION [346656-34-6]

Overview

MDLMFCD08276372
Molecular Weight262.11
Molecular FormulaC14H19BO4
SMILESO=C(OCC)C1=CC=CC=C1B2OCC(C)(C)CO2

For research use only. We do not sell to patients.

Summary

HSL-IN-3 (example 42), a boronic acid ester derivative, is an inhibitor of hormone-sensitive lipase (HSL) [1] .


IC50 & Target

HSL [1] .


Appearance

Liquid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 381.52 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8152 mL 19.0760 mL 38.1519 mL
5 mM 0.7630 mL 3.8152 mL 7.6304 mL
10 mM 0.3815 mL 1.9076 mL 3.8152 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (7.94 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (7.94 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (7.94 mM); Clear solution

* All of the co-solvents are available by MCE.