[CAS NO. 2623-22-5] 15-Acetoxyscirpenol

Name: 15-Acetoxyscirpenol
Brand: Arctom Scientific
SKU: HY-N6681

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PRODUCTS SPECIFICATIONS [2623-22-5]

Distributor

Catalog

HY-N6681

Brand

MCE

CAS

2623-22-5

DESCRIPTION [2623-22-5]

Overview

MDL	MFCD00078774
Molecular Weight	324.37
Molecular Formula	C17H24O6
SMILES	CC([C@]1(CC2)COC(C)=O)([C@@H]3O)C4(CO4)[C@@](O[C@]1([H])C=C2C)([H])[C@@H]3O

For research use only. We do not sell to patients.

Summary

15-acetoxyscirpenol, one of acetoxyscirpenol moiety mycotoxins (ASMs), strongly induces apoptosis and inhibits Jurkat T cell growth in a dose-dependent manner by activating other caspases independent of caspase-3 ^[1] .

IC50 & Target

Caspase

Appearance

Solid

Source

Fusarium poae

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

References

[1] Lee DH, et al. Induction of apoptosis by disturbing mitochondrial-membrane potential and cleaving PARP in Jurkat T cells through treatment with acetoxyscirpenol mycotoxins. Biol Pharm Bull. 2006 Apr;29(4):648-54.

Synonyms

Trichothec-9-ene-3,4,15-triol, 12,13-epoxy-, 15-acetate, (3α,4β)-

Trichothec-9-ene-3α,4β,15-triol, 12,13-epoxy-, 15-acetate

Scirp-9-ene-3α,4β,15-triol, 12,13-epoxy-, 15-acetate

15-Acetoxyscirpen-3,4-diol

4-Deacetylanguidin

NSC 267030

15-Acetoxyscirpenol

15-Monoacetoxyscirpenol

15-Mono-O-acetylscirpenol

15-O-Acetylscirpenetriol

15-Acetylscirpenetriol

Monoacetoxyscirpenol

Acetoxyscirpenediol