[CAS NO. 26020-14-4] Calenduloside E

Name: Calenduloside E
Brand: Arctom Scientific
SKU: HY-N6850

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PRODUCTS SPECIFICATIONS [26020-14-4]

Distributor

Catalog

HY-N6850

Brand

MCE

CAS

26020-14-4

DESCRIPTION [26020-14-4]

Overview

MDL	-
Molecular Weight	632.82
Molecular Formula	C36H56O9
SMILES	C[C@]12[C@]3(C([C@@]4([H])[C@](C(O)=O)(CCC(C)(C)C4)CC3)=CC[C@]1([H])[C@@]5([C@@](C(C)([C@@H](O[C@]6([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(O)=O)CC5)C)([H])CC2)C)C

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE

[1]J Mol Histol. 2022 Jul 12.

Summary

Calenduloside E (CE) is a natural pentacyclic triterpenoid saponin extracted from Aralia elata . Calenduloside E (CE) has anti-apoptotic potent by targeting heat shock protein 90 ( Hsp90 ) ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 158.02 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5802 mL	7.9011 mL	15.8023 mL
5 mM	0.3160 mL	1.5802 mL	3.1605 mL
10 mM	0.1580 mL	0.7901 mL	1.5802 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (3.95 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (3.95 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Tian Y, et al. The clickable activity-based probe of anti-apoptotic calenduloside E. Pharm Biol. 2019 Dec;57(1):133-139.

Synonyms

β-D-Glucopyranosiduronic acid, (3β)-17-carboxy-28-norolean-12-en-3-yl

Olean-12-en-28-oic acid, 3β-(β-D-glucopyranuronosyloxy)-

Glucopyranosiduronic acid, 3β-hydroxyolean-12-en-28-oic acid, β-D-

28-Noroleanane, β-D-glucopyranosiduronic acid deriv.

(3β)-17-Carboxy-28-norolean-12-en-3-yl β-D-glucopyranosiduronic acid

Calenduloside E

Oleanolic acid 3-O-β-D-glucuronopyranoside

Silphioside F

Polysciasaponin P₇

Momordin Ib

Oleanolic acid 3-O-glucuronide

3-O-(β-D-Glucopyranuronosyl)oleanolic acid

Glycoside St-E

28-Desglucosylchikusetsusaponin IVa

3β-Hydroxyolean-12-en-28-oic acid 3-O-β-D-glucuronide

Scheffleraside I

3-O-β-D-Glucuronopyranosyloleanolic acid