[CAS NO. 22467-07-8] Gymnemagenin
PRODUCTS SPECIFICATIONS [22467-07-8]
DESCRIPTION [22467-07-8]
Overview
| MDL | MFCD06656306 |
|---|---|
| Molecular Weight | 506.71 |
| Molecular Formula | C30H50O6 |
| SMILES | OC[C@]1([C@H]2O)[C@](CC(C)(C)[C@H]2O)([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(CC[C@H](O)[C@@]5(C)CO)C)[C@]3(C)C[C@@H]1O |
Summary
In Vivo
Gymnemagenin has a poor oral bioavailability (~ 14 %) in rats
[2]
.
Gymnemagenin has a short half-life and a high clearance in rats
[2]
.
Gymnemagenin metabolizes rapidly with a short apparent and intrinsic half-life (~ 7 min) and high intrinsic clearance
[2]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
References
- [1] Parthasarathy R, et al. Gymnemagenin-producing endophytic fungus isolated from a medicinal plant Gymnema sylvestre R.Br. Appl Biochem Biotechnol. 2014 Mar;172(6):3141-52.
- [2] In Vitro Metabolic Stability and Permeability of Gymnemagenin and Its In Vivo Pharmacokinetic Correlation in Rats - A Pilot Study.
