[CAS NO. 2237268-90-3] Nampt activator-2
PRODUCTS SPECIFICATIONS [2237268-90-3]
DESCRIPTION [2237268-90-3]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 390.84 |
| Molecular Formula | C17H15ClN4O3S |
| SMILES | O=C(NCC1=CNN=C1)NC2=CC=C(S(=O)(C3=CC=C(C=C3)Cl)=O)C=C2 |
Summary
In Vitro
Nampt activator-2 (compound 34) (10 μM, 4 h) results in a marked increase of both NMN and NAD in A549 lung epithelial cells [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Nampt activator-2 (compound 34) (1 mg/kg iv and 10 mg/kg po, once) shows low plasma clearance, good exposure and excellent oral bioavailability (%F = 80) [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
| Animal Model: | Mouse [1] | |||||||||||||||||||||
| Dosage: | 1 mg/kg iv and 10 mg/kg po | |||||||||||||||||||||
| Administration: | IV, PO; once (Pharmacokinetic Analysis) | |||||||||||||||||||||
| Result: |
Pharmacokinetic Parameters of Nampt activator-2 in mouse
[1]
.
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Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
