[CAS NO. 1740-19-8] Dehydroabietic acid

Name: Dehydroabietic acid
Brand: Arctom Scientific
SKU: HY-N6869

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PRODUCTS SPECIFICATIONS [1740-19-8]

Distributor

Catalog

HY-N6869

Brand

MCE

CAS

1740-19-8

DESCRIPTION [1740-19-8]

Overview

MDL	-
Molecular Weight	300.44
Molecular Formula	C20H28O2
SMILES	O=C([C@]1(C)CCC[C@]2(C)C3=C(CC[C@@]12[H])C=C(C(C)C)C=C3)O

For research use only. We do not sell to patients.

Summary

Dehydroabietic acid possesses antiviral activity ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 332.85 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3285 mL	16.6423 mL	33.2845 mL
5 mM	0.6657 mL	3.3285 mL	6.6569 mL
10 mM	0.3328 mL	1.6642 mL	3.3285 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: 2.5 mg/mL (8.32 mM); Suspended solution; Need ultrasonic
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: 2.5 mg/mL (8.32 mM); Suspended solution; Need ultrasonic
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (8.32 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Fonseca T, et al. Synthesis and antiviral evaluation of benzimidazoles, quinoxalines and indoles from dehydroabietic acid. Bioorg Med Chem. 2004 Jan 2;12(1):103-12.

Synonyms

1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)-

Abietic acid, dehydro-

Podocarpa-8,11,13-trien-15-oic acid, 13-isopropyl-

1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, [1R-(1α,4aβ,10aα)]-

(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic acid

Dehydroabietic acid

Abieta-8,11,13-trien-18-oic acid

(+)-Dehydroabietic acid

NSC 2952

Resigral 52

7-Callitrisic acid